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  • Mental health and psychosocial support
  • Research and analysis

Combining self-regulation and poverty reduction to prevent depression and anxiety among adolescents experiencing multi-dimensional poverty in Colombia, Nepal and South Africa: study protocol of a pilot 4-arm cluster randomised controlled trial

8 Jun 2026

A young boy smiles and shows his dirty palms to the camera inside a tent with a dirt floor.

Poverty is associated with depression and anxiety among adolescents, but evidence of interventions that prevent adolescent depression and anxiety among adolescents living in poverty is weak. Interventions either focus on reducing poverty or addressing depression and anxiety, but an approach that combines both may offer larger benefit.

Authors: Jordans, M. J. D., Lund, C., Garman, E. C., Seifert Bonifaz, M., Avendano, M., Bauer, A., Dedios Sanguineti, M. C., Eleftheriou, G., Evans-Lacko, S., Garcia Jaramillo, S., Garcia, J. F., Gautam, K., Gevonden, M., Jacobs, R., Kohrt, B. A., Krabbendam, L., Luitel, N. P., van der Merwe, N., Castellanos Piedrahita, J. J., Singh, R., Sinichi, M., Trujillo, D., Sorsdahl, K., Roy, S., Tol, W. A., Rojas, D., & Yarrow, P.

This multi-site parallel pilot cluster randomised controlled trial (cRCT) evaluates the feasibility and acceptability of a selective preventive intervention for depression and anxiety that simultaneously intervenes on both poverty and self-regulation among adolescents living in urban poverty.

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