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An App-Based WHO Mental Health Guide for Depression Detection: A Cluster Randomized Clinical Trial

23 May 2025

Depression detection in primary care remains limited in low- and middle-income countries despite increasing use of the World Health Organization Mental Health Gap Action Programme-Intervention Guide (mhGAP-IG).

Authors: Kohrt, B. A., Ojagbemi, A., Luitel, N. P., Bakolis, I., Bello, T., McCrone, P., Taylor Salisbury, T., Jordans, M. J. D., Votruba, N., Carswell, K., Green, E., Gkaintatzi, E., Lamichhane, B., Elugbadebo, O., Kola, L., Lempp, H., Chowdhary, N., Dua, T., Gureje, O., & Thornicroft, G.

What is the feasibility of using the World Health Organization’s mobile app version of the Mental Health Gap Action Programme–Intervention Guide (e-mhGAP-IG) to improve detection of depression? This cluster randomized clinical trial of 35 primary care facilities in Nepal and Nigeria found that in Nepal, the app was used rarely, and depression detection was poor for the standard mhGAP-IG and the e-mhGAP-IG. In Nigeria, the app was commonly used, with 88% of depression cases detected in the group using the e-mhGAP-IG compared with 33% of cases using the standard mhGAP-IG.

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